std symptoms can cause DNA damage that may increase the risk of later developing cancer, a new study suggests.
In the study, human cells growing in lab dishes that were infected with chlamydia were more likely to have DNA damage compared to cells not infected with chlamydia. What's more, this DNA damage was not always repaired properly by the cell, increasing the chances of genetic mutations.
Normally, cells with such DNA damage would activate a process that kills the cells, so that the cell does not turn cancerous. But in the study, the cells with DNA damage overrode this mechanism, and continued to divide. The continued division of cells with DNA mutations could eventually lead to cancer, the researchers said.
Earlier studies found an association between chlamydia infections and an increased risk of cervical and ovarian cancer in people, but such studies cannot prove cause and effect. The new study provides a biological explanation for how chlamydia could increase the risk of cancer.
However, because the study was conducted in cells in a lab dish, more research is needed to show the same thing occurs in people.
The new study, conducted by researchers at the Max Planck Institute for Infection Biology in Berlin, was published June 12 in the journal Cell Host & Microbe.
Chlamydia is a sexually transmitted disease caused by the bacteria Chlamydia trachomatis. Most infected people have no symptoms, according to the Centers for Disease Control and Prevention. However, untreated infections can damage the reproductive tract in women, and cause infertility. Complications from untreated infections are rare in men, but the condition can cause a burning sensation when urinating, and very rarely, prevent a man from fathering children, the CDC says.
Persistent infection by Chlamydia Treatment may increase the risk of cancer via damage to the DNA, according to a report published in the journal Cell Host & Damage. In addition to mutating host cell DNA, the disease also inhibits cellular mechanisms intended to repair the damage.
Researchers at the Max Planck Institute for Infection Biology in Berlin grew human cells in a lab, then infecting them with chlamydia. The group of cells infected were more likely to show damage than their uninfected counterparts.
The researchers also found that the damage done to the cells is similar to the damage done by cancer. Cells that did not simply die when infected went on to reproduce others imprinted with the same DNA damage.
In 2009, the Center For Disease Control reported that 84,000 women were diagnosed with a gynecologic cancer. It's unclear how many may have been linked with a chlamydia infection, but doctors urge women - who can host the disease for long periods of time with no symptoms - to get screened for it.
Do i have chlamydia is a world wide sexually transmitted disease. It affects over three million people each year. Actually, Chlamydia isn't danger, because its complications, many with painful, long-term effects, are the risks of our health. Since the complications of chlamydia are so dangerous, it's important to receive a diagnosis as early as possible. Here are five ways for you to learn to diagnose chlamydia by yourself.
chlamydia in men symptoms, as one of the most common sexually transmitted diseases in the United States, affects nearly four million people each year. It is easily spread because it often causes no symptoms and spread to sexual partners unknowingly. Since lots of men cannot experience any symptoms, 50% men also can experience some symptoms.
First, mall amounts of clear or cloudy discharge from the tip of penis. Second, painful urination Third, burning and itching around the opening of the penis Fourth, Pain and swelling around the testicles The above mentioned four symptoms are typical symptoms in men. Some may experience one; some may experience two; some may experience all, which depends on the degree of the condition. If you find that you have had those symptoms, the first thing you have to do is taking some tests. Your doctor, he or she will probably use a swab to take sample from the urethra in men and then will send the specimen to a lab to be analyzed. There also are other tests which check a urine sample for the presence of the bacteria. If you do have chlamydia, there is no need to worry about it, for this disease and its complications can be cured by herbal formula - Diuretic and Anti-inflammatory Pill . This pill made of more than 40 herbs, so it is safe and can be taken for a long time. This pill also has many amazing functions such as promoting blood circulation, dissipating hard lumps, clearing away heat and toxic materials and so on. if you are interested in it, please contact us as soon as possible.
More screenings may be the reason for an increase in the number of sexually transmitted diseases in 2011, particularly among men, says a report by the Centers for Disease Control and Prevention.
The annual all stds report, released in December 2012, shows more than 1.4 million chlamydia cases in 2011 — the largest number reported to the CDC for any condition — and an increase of 8% from 2010. From 2007 to 2011, the rate of chlamydia jumped 36% in men and 20% in women (cdc.gov/std/stats11/Surv2011.pdf).
"The continued increase in chlamydia case reports in 2011 most likely represents a continued increase in screening for this usually asymptomatic infection, expanded use of more sensitive tests and more complete national reporting, but it also may reflect a true increase in morbidity," study authors said in the report.
Gonorrhea and syphilis showed higher increases in men than women from 2010 to 2011. Gonorrhea rose 3% in women and 5% in men. Primary and secondary syphilis infection went up 4% in men but down 9% in women.
Better access to urine-based technology for chlamydia and gonorrhea is probably encouraging more men to be tested, said Arik V. Marcell, MD, MPH, an assistant professor in the Dept. of Pediatrics at Johns Hopkins University in Baltimore. These tests are more acceptable to men "rather than older swab collection techniques that were painful," he said.
Although syphilis cases reached historic lows in recent decades, the CDC report found men who have sex with men accounted for 72% of primary and secondary syphilis cases reported in 2011. Failing to obtain proper medical care is a likely contributor to the high numbers of syphilis infections in gay and bisexual men, said Hillard Weinstock, a medical epidemiologist in the CDC’s Division of STD Prevention.
"Risk behavior alone does not explain the disproportionate levels of infection among gay and bisexual men," Weinstock said. "Complex issues like homophobia and stigma also help fuel infection and can make it difficult for gay and bisexual men to seek appropriate care and treatment."
Americans ages 15 to 24 are at the highest risk for chlamydia, gonorrhea and syphilis, data show. Research finds that risky behavior, such as not wearing condoms, remains high among youths, Weinstock said.
"There is no one single explanation for the high levels of STD infections among youth," Weinstock said. "A complex combination of behavioral, biological and cultural factors place youth at a higher risk of acquiring STDs than adults."
Better patient assessments by primary care physicians can reduce the number of STDs, Dr. Marcell said. “Health care providers need to conduct comprehensive assessment with all patients, especially youth, for sexual behavior. This includes assessing for types of sexual activity; number of partners, including partner concurrency; use of contraception, including condoms;” and STD history.
Sexual health education also can be improved, he said.
"Promotion of sexual health and understanding of its consequences are critical for the nation, especially for young persons," he said. "This includes supporting comprehensive sex education in school and at home."